Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
+44 1223 790975
ISSN: 2155-6148
+44 1223 790975
Samer Fakhri
Tanzania
Research Article
Platelet Function as Affected by Total Intravenous and Inhalational Anesthesia
Author(s): Davide Cattano, Fernando Gomez-Rivera, Carmen Seitan, Alfonso V. Altamirano, Chirag B. Patel, Amber U. Luong, Martin J. Citardi, Samer Fakhri and Carin A. HagbergDavide Cattano, Fernando Gomez-Rivera, Carmen Seitan, Alfonso V. Altamirano, Chirag B. Patel, Amber U. Luong, Martin J. Citardi, Samer Fakhri and Carin A. Hagberg
Background: Few studies have attempted to demonstrate a benefit of a total intraveneous anesthesia (TIVA) as the sole technique to optimize and reduce bleeding. Also few reports have linked the use of propofol to platelet dysfunction, and while Thromboelastography (TEG®) has been used previously, its complement platelet mapping (PM™) has not. The aim of the study was to exclude different causes for blood loss during surgery, including drug effects on platelet function.
Methods: After IRB approval, we studied 23 patients scheduled to undergo endoscopic sinus surgery. Using a double-blind experimental method, we randomly assigned patients to receive either TIVA with propofol/remifentanil (PR) or inhalational anesthesia with sevoflurane/remifentanil (SR).
Results: Estimated blood loss (PR 152.9 ± 161.3 cc/SR 355.9 ± 393.4 cc) showed no significant .. View More»
DOI:
10.4172/2155-6148.1000290