Medical Safety & Global Health
Open Access

Rosell R

Publications

• Research Article
  Assay of Several Inactivation Steps on West Nile Virus and H7N1 Highly Pathogenic Avian Influenza Virus Suspensions
  Author(s): Xavier Abad Xavier Abad
  
  Objectives: In any research laboratory, precautionary measures must be taken in order to reduce or eliminate the potential risk of accidental infection by biosafety level 3 (BSL3) pathogens, as Highly Pathogenic Avian Influenza Virus (HPAI) or West Nile Virus (WNV). Appropriate virus inactivation procedures have to be set up to allow necessary further processing of specimens outside BSL3 facilities. Methods: To study the elimination of WN and HPAI virus infectivity, the effect of different chemical and physical inactivation procedures on viral suspensions were investigated. A proper cell culture assay for each virus was performed to verify several treatments, which are commonly performed preceding transfer of materials outside of biocontainment, still allowing further investigations like sequencing or genome amplification. .. View More»
  DOI: 10.4172/2167-0331.1000103

  Abstract PDF

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