Journal of Clinical Toxicology
Open Access
ISSN: 2161-0495
ISSN: 2161-0495
Rakesh Gami
College of Medicine,
St. Vincent and The Grenadines
Dominica
Review Article
Mad Honey Poisoning: A Review
Author(s): Rakesh Gami and Prajwal DhakalRakesh Gami and Prajwal Dhakal
Mad honey, which is different from normal commercial honey, is contaminated with grayanotoxins and causes intoxication. It is used as an alternative therapy for hypertension, peptic ulcer disease and is also being used more commonly for its aphrodisiac effects. Grayanotoxins, found in rhododendron plant, act on sodium ion channels and place them in partially open state. They also act on muscarinic receptors. Cardiac manifestations of mad honey poisoning include hypotension and rhythm disorders such as bradycardia, nodal rhythm, atrial fibrillation, complete atrioventricular block or even complete heart block. Additionally, patients may develop dizziness, nausea and vomiting, weakness, sweating, blurred vision, diplopia and impaired consciousness. Diagnosis is made with history of honey intake and clinical presentation. Treatment is symptomatic. Patients presenting with severe hypotens.. View More»
DOI:
10.4172/2161-0495.1000336