Anesthesia & Clinical Research

Anesthesia & Clinical Research
Open Access

ISSN: 2155-6148

R. Gopinath

  • Research Article
    Role of Steroids in Prevention of Pain on Propofol Injection
    Author(s): Monu Yadav, Padmaja Durga and R. GopinathMonu Yadav, Padmaja Durga and R. Gopinath

    Background and objectives: Pain following intravenous injection of propofol continues to be an intriguing problem. None of the commonly used methods completely attenuate the pain. Inflammatory response to propofol contributes to the pain. Role of hydrocortisone in attenuating pain has not been evaluated. This study was conducted to compare the efficacy of lignocaine and hydrocortisone in attenuation of pain following intravenous injection of propofol. Methods: A prospective randomized double-blind, placebo-controlled study was conducted on 72 adult patients belonging to ASA physical status I or II, scheduled to undergo elective surgery. They were randomly assigned into four groups of 18 each. Group NS, group LG, group HC10, and group HC25, received 2ml normal saline, 2ml 2% lignocaine, 10mg/2ml hydrocortisone and 25mg/2ml hydrocortisone resp.. View More»
    DOI: 10.4172/2155-6148.1000132

    Abstract PDF

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