Journal of Bone Research
Open Access

Peter W Zandstra

Biography

Peter W. Zandstra, Ph. D., FRSC, he is Professor of Tissue Engineering, and a Canada Research Chair in Stem Cell Bioengineering at the University of Toronto Institute of Biomedical Engineering, Orthopaedics, Bone marrow transplant

Research Interest

 Research in the Zandstra Laboratory is focused on the regeneration of functional tissues from stem cells and the development and utilization of tools to modulate the responses of stem cells in vitro and in vivo. Interest in the generation of primary cells and tissues ex vivo is driven both by their potential use as a direct clinical modality and as human tissue analogues for the development of novel therapeutic agents. Dr Zandstra’s group particularly interested in understanding the role that the extracellular environment, the stem cell niche, plays in controlling stem cell fate decisions. Using quantitative bioengineering approaches including micro-fabrication, bioreactors, mathematically modeling and protein and cell engineering the Zandstra lab is discovering how stem cells integrate their complex microenvironment to make self-renewal or differentiation divisions.

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