Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
+44 1223 790975
ISSN: 2155-6148
+44 1223 790975
Patrick A Ross
MD, Department of Anesthesiology Critical Care Medicine, Children’s Hospital Los Angeles, Mail Stop #12, 4650 Sunset Boulevard, Los Angeles, CA 90027,
Tanzania
Research Article
Tranexamic Acid Reduces PRBC Transfusion after Posterior Spine Surgery
for Idiopathic Scoliosis from the Operating Room to Post-Operative Day
Four
Author(s): Kim T Ngo, Robinder G Khemani, Paul D Choi and Patrick A RossKim T Ngo, Robinder G Khemani, Paul D Choi and Patrick A Ross
Background: Tranexamic acid (TXA), an antifibrinolytic, has been shown to reduce blood loss and packed red blood cell (PRBC) transfusion during surgery for patients with idiopathic scoliosis undergoing posterior spine fusion. Our goal was to determine if intra-operative TXA administration is also associated with reduced PRBC transfusion after the completion of surgery through post-operative day (POD) four in this patient population.
Methods: A retrospective review of 230 patients undergoing single stage PSF for idiopathic scoliosis at a freestanding children’s hospital was undertaken. Subjects were grouped according to intra-operative administration of TXA (n=70) or no TXA (n=160). The primary outcome was PRBC transfusion following surgery to post-operative day (POD) four. Secondary outcomes included estimated blood loss, intra-operati.. View More»
DOI:
10.4172/2155-6148.1000338