ISSN: 2155-6148
+44 1223 790975
Ottokar Stundner
Tanzania
Research Article
The Effect of Incremental Airway Resistance on Cardiac Performance and Pulmonary Pressure in Spontaneously Breathing Volunteers
Author(s): Thomas Danninger, Stephen Haskins, Ottokar Stundner, Yan Ma, Jemiel Nejim, Sean Garvin and Stavros G MemtsoudisThomas Danninger, Stephen Haskins, Ottokar Stundner, Yan Ma, Jemiel Nejim, Sean Garvin and Stavros G Memtsoudis
Previous research suggests that increases in airway resistance are associated with a depression in a number of hemodynamic variables. In this study we evaluated the hypothesis that these changes may be in part associated and explainable with increases in pulmonary vascular pressures. We therefore examined the effect of increasing airway resistance on a number of cardiac parameters, and estimated pulmonary arterial pressures using transthoracic echocardiography (TTE) in spontaneously breathing healthy volunteers.
Methods: Subjects were connected to a bioreactance monitor capable of determining hemodynamic parameters including stroke volume (SV), and cardiac index (CI). Blood pressure (NIBP) was obtained non-invasively. Volunteers sequentially breathed for 2 minutes through endotracheal tubes (ETT) with decreasing internal diameters (ID) between 8.0 and 3.0 mm.. View More»
DOI:
10.4172/2155-6148.1000360