Journal of Alcoholism & Drug Dependence
Open Access
ISSN: 2329-6488
+44 1223 790975
ISSN: 2329-6488
+44 1223 790975
Onyango TO
P.O. Box 43844-00100, Nairobi
Kenya
Research Article
Effects of Maalox Plus® Antacid and PureCal® Calcium Supplements on Haematological and Biochemical Parameters of Rats Subjected to Alcohol Intoxication
Author(s): Onyango TO, Mburu DN, Ngugi MP, Kamau JK and Juma KKOnyango TO, Mburu DN, Ngugi MP, Kamau JK and Juma KK
Habitual intake of alcohol is associated with health complications including depletion of the body’s stores of magnesium and calcium. In chronic alcoholism, treatment with magnesium and calcium has shown to normalize elevated enzyme activities and clinically relevant parameters. This study examined the effects of Maalox plus® antacid and PureCal® calcium which are rich in magnesium and calcium, respectively, on the haematological and biochemical profiles of rats exposed to acute alcohol intoxication. Alcohol was administered orally at a dosage 5 g/kg body weight for five days and supplements for two days of the week in duration of 28 days. Haematological and biochemical profiles were determined using automated analyzer. Statistical comparison was done using one way ANOVA followed by Tukey’s test. Alcohol caused neutrophilia, eosinophilia and b.. View More»
DOI:
10.4172/2329-6488.1000265