Journal of Clinical Toxicology
Open Access
ISSN: 2161-0495
ISSN: 2161-0495
Ngugi MP
Kenya
Review Article
Evidence Based Phytopharmacological Potential of Herbal Extracts in Post-Ingestion Management of Mycotoxins in Animal Models
Author(s): Juma KK, Fulakeza RMJ, Ngeranwa JN, Ngugi MP and Mburu NDJuma KK, Fulakeza RMJ, Ngeranwa JN, Ngugi MP and Mburu ND
Aflatoxins and ochratoxins are common mycotoxic food poisons and acute doses are responsible for causing liver and kidney damage and hepatocarcinoma. The strategy for managing mycotoxins has mainly been pre-ingestive. However, few solutions have been proposed for post-ingestion management and likewise there is no antidote for managing the condition. Studies have demonstrated that Saccharomyces cerevisiae and herbal extracts have potential of limiting the damage caused by reactive oxygen species and toxic effects associated with mycotoxins. Further evidence also shows that herbal extracts provides protection to a variety of cancer cell lines associated with mycotoxins. This study therefore examines the probable potential and options of using medicinal herbal extracts, on their own or in combinations with Saccharomyces cerevisiae, in the management of mycotoxicosis. A combination of the.. View More»
DOI:
10.4172/2161-0495.1000260