Journal of Hematology & Thromboembolic Diseases
Open Access
ISSN: 2329-8790
+44 1478 350008
ISSN: 2329-8790
+44 1478 350008
Muzaffer Demir A
Turkey
Research Article
Multiple Myeloma and Thromboembolism in the Perspective of Age and Performance
Author(s): Elif G Umit, Mehmet Baysal and Muzaffer Demir AElif G Umit, Mehmet Baysal and Muzaffer Demir A
Introduction: The relation with cancer and thromboembolism (TE) are well documented. Within cancer types, hematological malignancies, especially Multiple Myeloma (MM) show a propensity towards TE with its disease biology, disease burden and treatments. We aimed to evaluate the risk factors of TE and MM with a perspective of age and clinical performance. Methods: Data regarding Eastern Cooperative Oncology Group (ECOG) and Karnofsky performance scores, patient, disease and treatment related properties of patients with MM between 2010 and 2016 were recorded. Results: Of the 125 MM patients, 60 were female (48%) while 65 were male (52%). Median age was 65 years. TE was observed in 28 patients (22.4%). In patients <65 years, poor ECOG and Karnofsky scores were strongly related with TE (p values 0.003 and 0.000). Polypharmacy and LDH elevation were observed to be risk factors in all age.. View More»
DOI:
10.4172/2329-8790.1000267