Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
+44 1223 790975
ISSN: 2155-6148
+44 1223 790975
Montague ML
Consultant Otolaryngologist, University Department of Otolaryngology ,
The Royal Hospital for Sick Children 9 Sciennes Road, Edinburgh, EH9 1LF
Research Article
Does the Use of Topical Lignocaine Spray during Microlaryngeal
Surgery Under General Anaesthesia have Significant Clinical Benefit? - A
Prospective Double-Blind Randomized Placebo-Controlled Trial
Author(s): Montague ML, Vernham GA, Todd G and MacKenzie KMontague ML, Vernham GA, Todd G and MacKenzie K
Objective: To determine if topical lignocaine used during microlaryngeal surgery under general anaesthesia confers significant clinical benefit by reducing the pressor response and laryngospasm that often occur during recovery.
Study Design: Prospective double-blind randomised placebo-controlled trial in a UK Otolaryngology department. 85 patients undergoing elective microlaryngeal surgery receiving either 4 ml 4% lignocaine spray to the vocal cords and piriform fossae or 4 ml 0.9% saline spray to the same areas at induction of anaesthesia.
Methods: Primary outcome measures were pulse and blood pressure recorded immediately before spray application and at 5 minute intervals during recovery for 20 minutes and the degree of laryngospasm or cough (absent, mild, moderate, severe) recorded at the same intervals. Seconda.. View More»
DOI:
10.4172/2155-6148.1000436