Journal of Clinical Toxicology
Open Access
ISSN: 2161-0495
+44 1478 350008
ISSN: 2161-0495
+44 1478 350008
Mohammed Salhab
The Warren Alpert Medical School of Brown University,
Memorial Hospital of Rhode Island, 111 Brewster street Pawtucket, RI 02860
Tanzania
Case Report
Valopric Acid Intoxication Induced Hyperammonemic Encephalopathy in Setting of a Normal Liver Function
Author(s): Mohammed Salhab, Omair Tahir, Abdullah Quddus, Adil Bhutta and Taro MinamiMohammed Salhab, Omair Tahir, Abdullah Quddus, Adil Bhutta and Taro Minami
We present a case of acute valoproic acid intoxication induced hyperammonemia encephalopathy and coma in a young man with a remarkably normal liver function test. L-Carnitine was used in addition to supportive management.
Patient mental status improved within 24 hours and VPA and ammonia levels were declining until normalized. Serial liver function tests, including the synthetic functions, were performed and they were only remarkable for mildly elevated aspartate aminotransferase on presentation and were normal throughout the admission course... View More»
DOI:
10.4172/2161-0495.1000208