Journal of Plant Biochemistry & Physiology
Open Access
ISSN: 2329-9029
+44 20 3868 9735
ISSN: 2329-9029
+44 20 3868 9735
Mobassirul Islam M
Bangladesh
Research Article
Hypoglycemic and Hypolipidemic Potential of Nigella sativa L. Seed
Extract in Streptozotocin (STZ)-Induced Diabetic Rats
Author(s): Asaduzzaman M, Lutfun Nahar, Sohanur Rahman M, Mahadi Hasan, Anowara Khatun, Zinat Tamanna, Nazmul Huda, Fazley Rabbi M, Manobendro Nath Ray, Nur Islam M, Mobassirul Islam M, Maniruzzaman M and Mehfuz AlamAsaduzzaman M, Lutfun Nahar, Sohanur Rahman M, Mahadi Hasan, Anowara Khatun, Zinat Tamanna, Nazmul Huda, Fazley Rabbi M, Manobendro Nath Ray, Nur Islam M, Mobassirul Islam M, Maniruzzaman M and Mehfuz Alam
Diabetes mellitus (DM) is the most common metabolic disease worldwide. Multiple medications and side effects, the most significant and prevalent themes in diabetes mellitus ultimately determine novel directions and avenues in drug discovery. The objective of this study was to determine the effects of NS (Nigella sativa) L. Seed hydroalcholic Extract on hypoglycemic and hypolipidemic condition in Streptozotocin- induced diabetic rats. DM was induced by single intraperitoneal injection of freshly prepared Streptozotocin (STZ) (65 mg/kg body weight) solution. Mice were divided into six groups. This study was conducted for 28 days and blood glucose level was measured at 7 days interval. Hyperlipidemic was induced by mixture of cholesterol (1.5%) and cholic acid (0.5%) with diet of rats. At the end of the treatment, the blood glucose level and lipid profil.. Read More»
DOI:
10.4172/2329-9029.1000158
