Bacterial Paediatric Meningitis Laboratory Diagnosis.
Author(s): Gudza-Mugabe M, Robertson V, Mapingure MP, Mtapuri-Zinyowera S and Mavenyengwa RTGudza-Mugabe M, Robertson V, Mapingure MP, Mtapuri-Zinyowera S and Mavenyengwa RT
Introduction: Bacterial meningitis is one of the top ten causes of death amongst children under 5 years in Zimbabwe. Optimizing the identification of the etiologic agents of bacterial meningitis leads to better management of patients. The objective of this study was to compare the effectiveness of latex agglutination (LA), culture and Polymerase Chain Reaction (PCR) as diagnostic methods in the detection of Neisseria meningitidis, Streptococcus pneumoniae, Streptococcus agalactiae and Haemophilus influenzae in paediatric cerebral spinal fluids (CSF) specimens at Harare Children`s Hospital (HCH). Methodology: Specimens from 162 clinically suspected paediatric cases of bacterial meningitis were processed by cell count, Gram stain, culture, latex agglutination and PCR. Results: Forty-nine (30.2%) suspected cases were .. Read More»