Journal of Antivirals & Antiretrovirals
Open Access
ISSN: 1948-5964
ISSN: 1948-5964
Matsumura H
Japan
Editorial
Future Perspective of Nucleic Acid-based Detection of Dengue Virus and
its Serotypes
Author(s): Kaihatsu K, Harada E, Matsumura H, Takenaka A, Wichukchinda N, Sa-Ngarsang A and Nobuo KatoKaihatsu K, Harada E, Matsumura H, Takenaka A, Wichukchinda N, Sa-Ngarsang A and Nobuo Kato
Dengue is an arthropod-borne viral disease of tropical and subtropical areas. A research group has estimated that there are 390 million dengue infections per year, 96 million in whom symptoms manifest. The symptoms of a primary infection with dengue are usually mild and resolve with time, but secondary infection with dengue virus of a different serotype may lead to more severe symptoms such as dengue haemorrhagic fever (DHF) and dengue shock syndrome (DSS). No vaccine or antiviral drug is approved for the prevention or treatment of dengue diseases. Therefore, it is important to diagnose the infection and differentiate the serotypes as early as possible. Currently, immunochromatographic assays are used for the diagnosis of clinical specimen from dengue infected patients in hospital, since they can detect the target antigen within 15min without any facilities. On the other hand, nucleic.. View More»
DOI:
10.4172/jaa.1000e132