Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
+44 1223 790975
ISSN: 2155-6148
+44 1223 790975
Masato Nakasuji
Kansai Electric Power Hospital,
2-1-7 Fukushima, Fukushima-ku Osaka 553-0003
Japan
Case Report
Hypertonic Mannitol-Induced Hyperkalemia during Craniotomy
Author(s): Masato Nakasuji, Masataka Nomura, Miwako Yoshioka, Taeko Miyata, Norie Imanaka and Masuji TanakaMasato Nakasuji, Masataka Nomura, Miwako Yoshioka, Taeko Miyata, Norie Imanaka and Masuji Tanaka
We experienced two cases of mannitol-induced hyperkalemia during craniotomy for ruptured aneurysms. Hyperkalemia was first diagnosed by peaked T wave on the ECG. Serum potassium concentration in each patient was approximately 2 mEq/l higher than the baseline value, reaching 6.0 and 5.7 mEq/l, respectively, at 2 hours after completion of infusion of 45 and 30 g mannitol, respectively. Although the underlying mechanism was not elucidated, we recommend that patients with potassium concentration more than 4 mEq/l before infusion, should undergo repeated arterial blood gases analysis until at least 2 hrs after completion of mannitol infusion.
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DOI:
10.4172/2155-6148.1000299