Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
+44 1223 790975
ISSN: 2155-6148
+44 1223 790975
Marinna D Scarlett
Department of Surgery, University of the West Indies and University Hospital Surgery, Radiology, Anesthesia & Intensive Care, 29 Phadrian Avenue, Kingston, Kgn 6,
Jamaica
Research Article
The Effect of Dexamethasone on Post-operative Opioid Requirement in Patients who Underwent Gynecology Surgery at the University Hospital in
Jamaica
Author(s): Becky Jno-Baptiste, Marinna D Scarlett and Hyacinth E HardingBecky Jno-Baptiste, Marinna D Scarlett and Hyacinth E Harding
Background: The necessity to improve post-operative analgesia and hence patients’ satisfaction has been the driving force of the quest for easy-to-administer, cost effective and safe analgesic agents. Dexamethasone is a powerful anti-inflammatory, analgesic and anti-emetic agent, that has been found to decrease opioid use, yet improve post-operative analgesia in a wide range of surgical patients.
Objectives: To determine if a single dose of intravenous Dexamethasone (0.5 mg/kg, not exceeding 40 mg), administered preoperatively, decreased post-operative opioid requirements without adverse effects in a cohort of Jamaican patients. Study design: A randomized, single-centre, single-blinded study was conducted over a six (6) month period. Patients, 18-60 years, scheduled to undergo gynecological surgery under general anesthesia, were recruite.. View More»
DOI:
10.4172/2155-6148.1000470