Journal of Clinical Toxicology
Open Access

Maria Caterina Grassi

Publications

• Case Report
  Efficacy of First-Line Sodium Thiosulfate Administration in a Case of Potassium Cyanide Poisoning
  Author(s): Diletta Sabatini, Andrea Giampreti, Paolo Mazzini, Carla Caranti, Antonella Valli and Maria Caterina GrassiDiletta Sabatini, Andrea Giampreti, Paolo Mazzini, Carla Caranti, Antonella Valli and Maria Caterina Grassi
  
  Cyanide poisoning may occur following accidental fire-smoke inhalation or deliberate ingestion of salts. Hydroxocobalamin represents a first-line life-saving antidote. Although hydroxocobalamin represents a first-line lifesaving antidote, it is still not promptly available in the emergency department. Sodium thiosulfate can be administered in association with hydroxocobalamin whereas the delayed onset of clinical response makes sodium thiosulfate less suitable for emergency use. We describe a case of cyanide intoxication of a 43-year-old man who ingested an unknown amount of potassium cyanide, purchased via the Internet, in an attempted suicide. At admission to the emergency department, the patient presented GCS 3 with severe lactic acidosis. Orotracheal intubation, gastric lavage and oral activated charcoal were applied. Sodium thiosulfate was available in the emergency department an.. View More»
  DOI: 10.4172/2161-0495.1000255

  Abstract PDF

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