Anesthesia & Clinical Research
Open Access

Marcello Migliore

Publications

• Research Article
  Dose-Response of Propofol for Tracheal Intubation in Children Correlated to Intubation Condition Score and Cerebral State Index. Randomized, Double-Blinded Trial
  Author(s): Carmelo Minardi, Marinella Astuto, Concetta M. Spinello, Laura Pagano, Sarah Pellegrino, Concetta Gullo, Francesco Perna, Stissi Carmela, Filippo Palermo, Paolo Murabito, Marcello Migliore and Antonino GulloCarmelo Minardi, Marinella Astuto, Concetta M. Spinello, Laura Pagano, Sarah Pellegrino, Concetta Gullo, Francesco Perna, Stissi Carmela, Filippo Palermo, Paolo Murabito, Marcello Migliore and Antonino Gullo
  
  Background: Avoiding neuromuscular blocking drugs may prevent the potential complications of their use if they are not required for the planned procedure. This study was designed to estimate dose-response of propofol for tracheal intubation in children correlated to Intubation Condition Score and Cerebral State Index (CSI) without neuromuscular blocking drugs. Methods: 56 children (ages 3-8 years), ASA physical status I and II, weight 13-35 Kg, admitted for adenotonsillectomy were included. Children were randomly divided into four groups to receive propofol by Target Controlled Infusion (TCI) at different concentrations: 3.0 μg•ml-1, 3.5 μg•ml-1, 4.0 μg•ml-1, 4.5 μg•ml-1. At time T0 remifentanil infusion 0.5 μg•kg-1•min-1 was started. After 4 min, time T1, children received propofol according to their group. At time T2 (8 min after T0) trac.. View More»
  DOI: 10.4172/2155-6148.1000202

  Abstract PDF

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