Anesthesia & Clinical Research
Open Access

Mamta Singh

Publications

• Research Article
  Ropivacaine Decreases Tissue Oxygen Saturation Following Peripheral Nerve Block in Children
  Author(s): Nina Deutsch, Mamta Singh, Sophie R. Pestieau, Sean P. Alexander, Domiciano Santos and Richard J. Levy Nina Deutsch, Mamta Singh, Sophie R. Pestieau, Sean P. Alexander, Domiciano Santos and Richard J. Levy
  
  Background: Local anesthetics can cause vasoconstriction and disrupt neuronal impulses, reducing regional blood flow and increasing tissue oxygen consumption. This could alter regional oxygen supply and demand. Because microcirculation modifies during development and oxygen consumption kinetics differ between children and adults, we aimed to assess effects of ropivacaine Peripheral Nerve Block (PNB) on regional tissue saturation in children and young adults using Near-Infrared Spectroscopy (NIRS). Methods: Following Institutional Review Board approval and informed consent, 20 patients undergoing PNB for various orthopedic surgeries were studied. NIRS sensors were placed on the operative limb, contralateral limb, and forehead. Tissue saturations (rSO2) were recorded at baseline and every 5 minutes for 60 minutes following ropivacaine PNB. Mea.. View More»
  DOI: 10.4172/2155-6148.1000301

  Abstract PDF

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