Cell & Developmental Biology

Cell & Developmental Biology
Open Access

ISSN: 2168-9296

+12 184512974

Jyotshna Kanungo

Jyotshna Kanungo
National Center for Toxicological Research,
U.S. Food and Drug Administration, 3900 NCTR Road

  • Editorial
    DNA Repair Defects and DNA-PK in Neurodegeneration
    Author(s): Jyotshna KanungoJyotshna Kanungo

    Mammalian brain consists of two major types of cells, the neurons and glia. Mature neurons are essentially post-mitotic and do not proliferate whereas some glial cells can undergo replication especially as a response to stress or damage [1,2]. Nervous system is one of the earliest systems to develop and differentiate in almost all the species. Therefore, literally, neurons in the brain are one of the oldest cell populations in the organism. Neurons are also one of the most metabolically active cells and gene expression is two- to threefold higher in neurons than in any other cell [3]. These non-dividing, metabolically hyperactive cells are, therefore, vulnerable to risks that involve DNA damage. .. Read More»
    DOI: 10.4172/2168-9296.1000e105

    Abstract PDF

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