Anesthesia & Clinical Research
Open Access

Jin-Yi Chen

Publications

• Research Article
  Residual Neuromuscular Blockade at Extubation: A Randomized Comparison of Sugammadex and Neostigmine Reversal of Rocuronium-Induced Blockade in Patients Undergoing Abdominal Surgery
  Author(s): Daniel Sabo, R. Kevin Jones, James Berry, Tod Sloan, Jin-Yi Chen, Jovino B Morte and Scott Groudine Daniel Sabo, R. Kevin Jones, James Berry, Tod Sloan, Jin-Yi Chen, Jovino B Morte and Scott Groudine
  
  Background: Residual neuromuscular blockade (NMB) is associated with increased risk of post-operative critical respiratory events. We compared incidence of residual NMB at tracheal extubation after reversal of rocuroniuminduced NMB with sugammadex versus neostigmine. Methods: Adult patients of American Society of Anesthesiologists Class 1-3, scheduled to undergo open abdominal surgery were included. Patients were randomized to receive sugammadex 4.0 mg/kg at ≥1-2 posttetanic counts after last rocuronium dose, or neostigmine 50mg/kg + glycopyrrolate 10mg/kg, according to usual care practices at each institution. Neuromuscular function was assessed using TOF-Watch® SX. Anesthesiologists were blinded to the TOF-Watch recording, except to ask the TOF-Watch operator whether ≥1 PTC had been reached before administering reversal. Use of a.. View More»
  DOI: 10.4172/2155-6148.1000140

  Abstract PDF

Relevant Topics