Angiology: Open Access
Open Access
ISSN: 2329-9495
+44 1478 350008
ISSN: 2329-9495
+44 1478 350008
Gaoliang Yan
Zhongda Hospital of Southeast University Medical School,
Nanjing
China
Research Article
Effect of Enalapril and Folic Acid Tablet on Contrast-induced Nephropathy in Patients with Mild Renal Insufficiency
Author(s): Chengchun Tang, Gaoliang Yan, Jiantong Hou, Xiaodong Pan, Zhongpu Chen, Chunju Yuan, Qianxing Zhou and Genshan MaChengchun Tang, Gaoliang Yan, Jiantong Hou, Xiaodong Pan, Zhongpu Chen, Chunju Yuan, Qianxing Zhou and Genshan Ma
Background:Currently, the role of angiotensin converting enzyme inhibitor (ACEI) or angiotensin receptor antagonist (ARB) in CIN is paradoxical due to important differences in study design and study participant characteristics. We speculated that enalapril and folic acid tablets may have better protection on kidney target. Aim: To explore the impact of enalapril and folic acid tablet on contrast-induced nephropathy (CIN) in patients with mild renal insufficiency after percutaneous coronary intervention (PCI).
Method: A total of 816 patients undergoing selective PCI, between January 2013 and December 2016, were enrolled in a prospective cohort. Patients were divided into enalapril and folic acid tablets treatment group (n=233) (Namely, intervention group) and non ACEI/ARB treatment group (n=583) (Namely, control group). Baseline data were com.. View More»
DOI:
10.4172/2329-9495.1000217