Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Ersilia Tolino
Dermatology Unit “Daniele Innocenzi”, “Sapienza” University of Rome, A. Fiorini Hospital,
via Firenze, snc 04019, Terracina (LT)
Italy
Research Article
Gender Matter in Isotretinoin Therapy for Acne Vulgaris? A Retrospective Study
Author(s): Nevena Skroza, Riccardo Pampena, Ersilia Tolino, Sara Zuber, Giorgio La Viola, Nicoletta Bernardini, Ilaria Proietti, Veronica Balduzzi, Fowzieh Rasras and Concetta PotenzaNevena Skroza, Riccardo Pampena, Ersilia Tolino, Sara Zuber, Giorgio La Viola, Nicoletta Bernardini, Ilaria Proietti, Veronica Balduzzi, Fowzieh Rasras and Concetta Potenza
Introduction: Gender differences have been recently highlighted for several aspects of acne vulgaris such as epidemiology, pathogenesis, clinical course, quality of life and treatment outcome. In particular a shorter but more severe clinical course has been reported in males than in females; nevertheless, usually men have their quality of life less affected.
Aim: To determine if the response and the adverse events to 1 cycle of oral isotretinoin therapy can be influenced by gender.
Methods: A retrospective study was conducted on consecutive patients affected by acne vulgaris and treated with oral isotretinoin. Global acne grading system (GAGS), acne-related quality of life (AQoL) and isotretinoin-related adverse events were considered as outcome measures and were evaluated before (T0), every month during administra.. View More»
DOI:
10.4172/2155-9554.10000300