These drugs interfere with enzymes called topoisomerases, which help separate the strands of DNA so they can be copied during the S phase. (Enzymes are proteins that cause chemical reactions in living cells.) Topoisomerase inhibitors are used to treat certain leukemias, as well as lung, ovarian, gastrointestinal, and other cancers.Topoisomerase inhibitors can be classified according to which type of enzyme they affect: Topoisomerase I inhibitors include: Topotecan, Irinotecan (CPT-11). Topoisomerase II inhibitors include: Etoposide (VP-16), Teniposide, Mitoxantrone (also acts as an anti-tumor antibiotic).
Related journals of Topoisomerase Inhibitors
Cancer Medicine & Anti Cancer Drugs, Agri, Food & Aqua Journals, Biochemistry Journals, Business & Management Journals, Chemical Engineering Journals, Journals on Clinical Sciences, Cancer Genomics and Proteomics, Journal of Cancer Research and Clinical Oncology, Translational Oncology, Cancer Epidemiology, Clinical Lung Cancer, International Journal of Oncology, Cancer Research and Treatment, European Journal of Cancer Prevention.