The purine antagonists function by inhibiting DNA synthesis in two different ways They can inhibit the production of the purine containing nucleotides, adenine and guanine. If a cell doesn't have sufficient amounts of purines, DNA synthesis is halted and the cell cannot divide.They may be incorporated into the DNA molecule during DNA synthesis. The presence of the inhibitor is thought to interfere with further cell division.
Related journals of Purine Antagoinsts for Cancer
Cancer Medicine & Anti Cancer Drugs, Journal of Integrative Oncology, Journal of Oncology Translational Research, Oncology & Cancer Case Reports, Journal of Neuro Oncology, Treatment Cancer Prevention Research, Cell death & disease, Seminars in Radiation Oncology, Frontiers in Oncology, Targeted Oncology, Current Cancer Drug Targets, Cellular Oncology.