Anesthesia & Clinical Research
Open Access

Duo Yang

Publications

• Research Article
  Intranasal Dexmedetomidine in Termination of First Trimester Pregnancy of Suction Evacuation
  Author(s): Hang Shi, Duo Yang and Jie LiuHang Shi, Duo Yang and Jie Liu
  
  Background and aim: Deep sedation without intubation for termination of first trimester pregnancy of suction evacuation entails use of sedatives such as propofol or a combination of propofol and sulfentanil, with unwanted complications. Dexmedetomidine is a α2-adrenorecepter agonist which provides sedation, anxiolysis and analgesia, without any of the complications associated with the popular sedatives. Methods: A total number of 90 patients were randomized to three groups: 1. Group P, treated with intranasal saline, intravenous saline and propofol; 2. Group DP, treated with intranasal dexmedetomidine, intravenous saline and propofol; and 3. Group SP, treated with intranasal saline, intravenous sulfentanil and propofol. The primary outcome was the consumption of propofol, and the secondary outcomes were numeric rating scale (NRS) anxiety .. View More»
  DOI: 10.4172/2155-6148.1000781

  Abstract PDF

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