Journal of Hematology & Thromboembolic Diseases
Open Access
ISSN: 2329-8790
+44 1478 350008
ISSN: 2329-8790
+44 1478 350008
Dulicek P
University Hospital and Charles University,
Hradec Kralove
Czech Republic
Research Article
Thrombophilia Work-up in Females with Venous Thromboembolism in Association with Oral Contraceptive Use: Results, Strategy and Clinical Application of Testing
Author(s): Dulicek P, Sadilek P, Beranek M, Ivanova E and Hirmerova JDulicek P, Sadilek P, Beranek M, Ivanova E and Hirmerova J
Background: Oral contraceptive use is one of the most common causes of venous thromboembolism in females in a reproductive age. The usefulness of thrombophilia work-up in this scenario has been discussed in the last years especially in the term of financial cost and clinical implication. In the case of testing, it is necessary to keep appropriate timing and conditions for every assay. Methods: We analyzed thrombophilia work-up in a large cohort of 700 females with venous thrombosis in association with combined contraceptive pills use. We focused on laboratory thrombophilia work-up in the term of an appropriate strategy of testing, the influence of oral contraceptives use, presence of acute thrombosis and type of anticoagulation therapy.
Results: We found high frequency of inherited thrombophilia and antiphospholipid syndrome in our study group .. View More»
DOI:
10.4172/2329-8790.1000275