Medical Safety & Global Health
Open Access
ISSN: 2574-0407
+44-20-4587-4809
ISSN: 2574-0407
+44-20-4587-4809
Ducruet T
Canada
Research Article
Patterns of Antipsychotic use Among Community-Dwelling Elderly Patients with Dementia: Impact of Regulatory Warnings
Author(s): Craig C, Tannenbaum C, Ducruet T and Moride YCraig C, Tannenbaum C, Ducruet T and Moride Y
Purpose: In Canada, regulatory warnings on cerebrovascular effects of risperidone and olanzapine in the elderly population with dementia were issued, respectively, in 2002 and 2004, and those on mortality associated with all atypical antipsychotics (APs) in 2005. These warnings led to a decrease in the prescription of APs, but effects on patterns of usage remain poorly examined. We conducted a study to assess the association between warnings and patterns of AP use in a population of community-dwelling elderly with dementia.
Methods: A retrospective cohort of 10,969 community-dwelling elderly (age 66+) with dementia who were new users of APs between 1st January 2000 and 31st December 2009 was assembled through the Quebec drug claims database (RAMQ). Association between regulatory warnings and rate of initiation of AP treatment was evaluated thr.. View More»
DOI:
10.4172/2574-0407.1000129