Christina M. Annunziata

Christina M. Annunziata

Medical Oncology Branch, National Cancer Institute, 10 Center Drive, Magnuson Cancer Center, National Cancer Institute, National Institutes of Health, Bethesda.

Biography

Dr. Annunziata established mechanisms underlying NF-kappaB molecular signal transduction in ovarian cancer. Her genomic profiling and functional screens identified both downstream targets and upstream regulators of this pathway, defining subgroups of patients whose cancers depend on NF-kappaB, and opening up possibilities for novel therapies to treat ovarian cancer. Her clinical trials emphasize collection of patient samples to better understand both predictive and pharmacodynamic markers of treatment response.

Research Interest

Proteasome; Bortezomib; Multiple Myeloma; Cytotoxic; Immunotherapy

Journal of Cell Science & Therapy
Open Access