Journal of Clinical Toxicology
Open Access
ISSN: 2161-0495
ISSN: 2161-0495
Chidi Uzoma Igwe
Owerri, Imo State
Nigeria
Research Article
Effect of Ethanol Leaf Extract of Moringa oleifera on Oxidative Stress and
Atherogenic Indices of Otapiapia-Exposed Albino Rats
Author(s): Chidi Uzoma Igwe, Linus Nwaogu, Emeka Ezeokeke, Callistus Iheme and LN AlisonChidi Uzoma Igwe, Linus Nwaogu, Emeka Ezeokeke, Callistus Iheme and LN Alison
Objective: Otapiapia is a locally produced, easily accessible, non-regulated household pesticide, which could easily contaminate human food. The ameliorative effect of ethanol leaf extract of Moringa oliefera on otapiapiainduced changes in oxidative stress, lipid profile and atherogenic indices of albino rats was investigated using standard methods.
Methodology: Twenty-four apparently healthy Wister male albino rats (150-180 g) were divided into 4 groups (IIV) of 6 animals each. Group I served as the control, while group II animals were given otapiapia contaminated feed and distilled water. Group III were fed uncontaminated diet and M. oleifera extract drink. Group IV animals were also given the contaminated diet and M. oliefera extract. The feed and drinks were provided ad libitum for a period of 14 days.
Result: .. View More»
DOI:
10.4172/2161-0495.1000350