Journal of Clinical Toxicology
Open Access
ISSN: 2161-0495
ISSN: 2161-0495
Brijyog
Institute of Pharmacy, HCPG College,
Varanasi, Uttar Pradesh-221002
India
Research Article
Antidiabetic Activity of Newly Formulated Oral Polyherbal Tablets in Alloxan Induced Diabetic Rats
Author(s): Brijyog, Ashish Sarkar, Sushil Kumar and Shweta VermaBrijyog, Ashish Sarkar, Sushil Kumar and Shweta Verma
Anacardium occidentale, Aegle marmelos and Achyranthes aspera are the medicinal plant and used for the treatment of diabetes mellitus. There is major challenge in bioavailability of herbal products when administered in raw form, and it can be overcome in the form of polyherbal tablets. In the present study polyherbal tablets were prepared using hydroalcoholic extracts of Anacardium occidentale (bark), Aegle marmelos (leaves) and Achyranthes aspera (aerial parts) by dry granulation method for the management of diabetes. Tablets were prepared and evaluated by using weight variation, hardness, and friability and disintegration time. The optimized formulation was investigated the antidiabetic activity in Alloxan-induced diabetic albino rats. Fasting blood glucose level and changes in body weight were measured on days 0, 8 and 15. At the end of .. View More»