Anesthesia & Clinical Research

Anesthesia & Clinical Research
Open Access

ISSN: 2155-6148

+44 1223 790975

Ashraf S Hasanin

  • Research Article
    Effectiveness of Dexmedetomidine as an Adjunct Agent for Sedation during ERCP
    Author(s): Fatma M Mahmoud, Ashraf S Hasanin and Wael Abdel-RazekFatma M Mahmoud, Ashraf S Hasanin and Wael Abdel-Razek

    Objectives: To evaluate dexmedetomidine as an adjunct drug to propofol for sedation during ERCP, and its effects on perfusion index (PI) which could be used as an indicator for analgesia level. Methods: 76 patients ASA (I-III) scheduled for ERCP procedure were randomly classified to either dexmedetomidine/propofol group or propofol group. In dexmedetomidine/propofol group, sedation was induced by dexmedetomidine (0.7 μg/kg) and propofol (50 mg) followed by infusion of dexmedetomidine (0.4 μg/kg/h) and propofol (0.5-1 mg/kg/h). In propofol group, sedation was induced by propofol (50 mg) followed by propofol infusion (0.5-1 mg/kg/h). HR, SBP, DBP, RR, SPO2 and PI were continuously monitored and recorded at the time points (T0 to T8). Results: Comparing dexmedetomidine/propofol group versus propofol group; PI values showed significant increase at T2 to T7 (p˂0.001), HR values show.. View More»
    DOI: 10.4172/2155-6148.1000599

    Abstract PDF

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