Journal of Cell Science & Therapy
Open Access
ISSN: 2157-7013
+44 1300 500008
ISSN: 2157-7013
+44 1300 500008
Antonio Giovanni Solimando
Section of Internal Medicine “G. Baccelli”, University of Bari Medical School,
Policlinico, Piazza Giulio Cesare 11, 70124 Bari
Italy
Case Report
Dyspnea, Fatigue, and Generalized Weakness in a 67-Year-Old Man:
Approach to the Patient Between Guidelines and Clinical Judgment
Author(s): Antonio Giovanni Solimando, Antonella Argentiero, Peter Kraus, Anna Ruckdeschel, Claudia Covelli, Angelo Vacca and Hermann EinseleAntonio Giovanni Solimando, Antonella Argentiero, Peter Kraus, Anna Ruckdeschel, Claudia Covelli, Angelo Vacca and Hermann Einsele
Mucormycosis are an emerging group of life-threatening fungal infections caused by filamentous fungi of the Mucorales family. Mucormycosis are most common in stem-cell transplant recipients and patients with underlying hematologic malignancies, poorly controlled diabetes mellitus, trauma, neutropenia, corticosteroid and deferoxamine therapy due to deficiency of phagocytic function, elevated serum levels of available iron and host-pathogen interaction. The fungi penetrate blood vessels causing endothelial damage and extensive angioinvasion with infarction, necrosis, and thrombosis of different tissues. Mucormycosis carries a very high mortality in cases of pulmonary disease, with even higher rates when there is difficulty establishing the diagnosis. We present a case of 67-year-old man with pulmonary form of mucormycosis presenting as opportunistic infection post induction chemotherapy.. View More»
DOI:
10.4172/2157-7013.1000258