Journal of Hematology & Thromboembolic Diseases

Journal of Hematology & Thromboembolic Diseases
Open Access

ISSN: 2329-8790

+44 7868 792050

Ali Ghasemi

Ali Ghasemi

West Indies

  • Review Article
    The Current Role of Bone Marrow Transplantation in the Treatment of Hemophilia A
    Author(s): Hassan Mansouritorghabeh and Ali GhasemiHassan Mansouritorghabeh and Ali Ghasemi

    Bone marrow transplantation (BMT) is nowadays used in various hematological disorders including leukemias. Hemophilia A is sex linked bleeding disorder in which there are various genetic abnormalities in factor VIII gene. Among various hematological disorders, bleeding disorders mainly hemophilia in now widely treated using plasma derived and recombinant factor VIII concentrates. Day to day transfusion of coagulation factor VIII in current lifelong disorder is a burden for the patients and decreases their quality of life. Although infection of coagulation products with blood-borne viruses that was major concern in treatment of hemophilia has been eliminated nearly complete at the present time, but appearance of factor VIII inhibitor is huge burden in treatment of hemophilia for both clinicians and patients. In this day and age BMT has gathered new insight and acceptable treatment for .. View More»
    DOI: 10.4172/2329-8790.1000143

    Abstract PDF

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