ISSN: 2155-6148
+44 1223 790975
Alexander A. Vitin
P.O.Box 356540, University of Washington, UWMC, 1959 NE Pacifi c, Seattle, WA 98195
Tanzania
Research Article
Effects of Vasoactive Agents on Blood Loss and Transfusion Requirements During Pre-Reperfusion Stages of the Orthotopic Liver Transplantation
Author(s): Alexander A. Vitin, Kenneth Martay, Youri Vater, Gregory Dembo and Marlena MaziarzAlexander A. Vitin, Kenneth Martay, Youri Vater, Gregory Dembo and Marlena Maziarz
Objective: To evaluate the effects of vasoactive drugs, specifi cally low-dose vasopressin and phenylephrine infusions, on blood loss / transfusion requirements during dissection and anhepatic (pre-reperfusion) stages of orthotopic liver transplantations.
Methods: A retrospective analysis of 110 orthotopic liver transplantation (OLT) cases was performed. The variables studied were: blood loss before and after reperfusion of the liver graft; blood volumes returned by cell-saver and amounts of transfused blood products; amounts of infused colloids and crystalloids; hemodynamic parameters such as MABP, MPAP, CO/CI, SVR; dosage of vasoactive drugs. Short – and long-term outcome measures included length-of stay (LOS), ICU LOS, 48 –hours return to the OR rate, incidence of the primary non-function of the liver graft, amounts of fresh f.. View More»
DOI:
10.4172/2155-6148.1000104