Anesthesia & Clinical Research
Open Access

Alaa M Atia

Publications

• Research Article
  Traumatic Brain Injury: Treatment with Mild Prolonged Hypothermia
  Author(s): Alaa M Atia and Khaled A Abdel-RahmanAlaa M Atia and Khaled A Abdel-Rahman
  
  Introduction: Hypothermia has been used as a method of brain protection in patients with traumatic brain injury (TBI) for many years. The protective effects of hypothermia are related to the inhibition of the excitatory amino acids (EAA) release including glutamate. The hypothermic decline of the cerebral metabolic rate of oxygen is also another mechanism of brain protection because it maintains the aerobic metabolism of the brain. Aim of the work: To study the effect of mild hypothermia on the outcome and complications in severe head trauma. Patients and methods: Ninety four patients (16-60 years old) with severe head trauma (Glasgow coma scale ≤ 8) were classified into hypothermic group (n=47) and normothermic group (n=47). The jugular venous bulb oxygen saturation, the jugular venous lactate, the Glasgow outcome scale at hospital discharge (GOS-HD), the length of ICU stay and ot.. View More»
  DOI: 10.4172/2155-6148.1000645

  Abstract PDF

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