Anesthesia & Clinical Research

Anesthesia & Clinical Research
Open Access

ISSN: 2155-6148

Akiyoshi Kuji

Publications
  • Research Article
    Evaluation of Transcutaneous and End-Tidal Carbon Dioxide During Intravenous Sedation in Volunteers
    Author(s): Kenichi Satoh DDS, Hitoshi Miura, Miho Kumagai, Masahito Satoh, Akiyoshi Kuji and Shigeharu JohKenichi Satoh DDS, Hitoshi Miura, Miho Kumagai, Masahito Satoh, Akiyoshi Kuji and Shigeharu Joh

    Objective: During intravenous sedation, end-tidal carbon dioxide (ETCO2) is usually measured with a nasal cannula or mouth-nose cannula. We compared the measurement accuracy of ETCO2 between these two devices and TC-CO2 and assessed which device is more useful during intravenous sedation in volunteers. Methods: Eight male volunteers aged 25 to 35 years were evaluated in this single-institution blinded observational trial. After they lay quietly for 5 min without supplemental oxygen, the volunteers received supplemental oxygen by means of each device at a flow rate of 3 L/min for 15 min. Next, midazolam (0.05 mg/kg) was intravenously injected, flumazenil (20 mg) was injected 30 min later, and the ETCO2 and TC-CO2 waveform were recorded. Results: The differences between ETCO2 and TC-CO2 significantly increased after mida.. View More»
    DOI: 10.4172/2155-6148.1000460

    Abstract PDF

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