Pediatrics & Therapeutics
Open Access
ISSN: 2161-0665
+44 1478 350008
ISSN: 2161-0665
+44 1478 350008
Mohsen Sedighi
Iran University of Medical Sciences, Iran
Posters & Accepted Abstracts: Pediatr Ther
Arterial switch operation (ASO) has been a routine technique for simple TGA repair that restores the left ventricle (LV) function before involution. With regard to impact of surgical time on clinical outcome of TGA repair, 105 patients with simple TGA underwent ASO. Th e patients were divided into three groups. Group A (n=33) included infants who underwent intervention during the fi rst week of life. Group B (n=35) and C (n=37) included the patients who underwent intervention during the second and third weeks of life, respectively. 82 patients received preoperative E1-prostaglandin and 14 patients underwent balloon atrial septostomy. Th e incidence of LV dysfunction (7 versus 0 and 3, P=0.02) and mortality rate (8 versus 1 and 3, P=0.04) were signifi cantly higher in patients of group C compare to A and B, respectively. Th ere was a remarkable diff erences among the B and C groups compare to group A regarding duration of inotropic support (2.4�?±0.08 and 2.6�?±0.08 versus 1.8�?±0.1 days, P=0.001) and intensive care unit stay (8.4�?±0.57 and 9.7�?±.64 versus 6.6�?±0.21 days, P=0.001). Arterial switch operation for patients with simple TGA still can be tolerated beyond the fi rst month of life. We recommend that simple TGA in neonates should be operated as soon as possible aft er birth.
Mohsen Sedighi is currently pursuing PhD in Neuroscience from Iran University of Medical Sciences, Iran. He has been in collaboration with Chamran Heart Center since 2010 and published several papers related to congenital heart surgery in reputed journals and participated in several international cardiovascular congresses.