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Hamed Mirhosseini and Teza Alfindo Bin Rosyid
Universiti Putra Malaysia, Malaysia
Posters-Accepted Abstracts: J Prob Health
Vitamins are essential elements affecting directly or indirectly in many biological regulating processes. As stated by FAO/WHO, the vitamin deficiency (VD) is a worldwide micronutrient deficiency disease. Vitamin A deficiency (VAD) is serious public health problem in developing countries such as Malaysia. Vitamin A derivatives play a role in regulation of nerve cell differentiation and development, also participate in numerous cellular functions including reproduction, development, vision, growth, lipid metabolism, cellular differentiation, proliferation, brain function and tissue maintenance. Widely, many people who suffer from VAD. This indicates that there is a lack of sufficient knowledge on the actual mechanisms of release, bioavailability and digestibility of vitamin A in human body digestive system. Thus, knowledge about the mechanisms of absorption of vitamin A can lead to better approaches for enhancing its absorption and could be helpful in ameliorating some of the deficiencies. However, the poor water solubility of all fat soluble vitamins is one of the main issues resulting in their low bioavailability and weak absorption. On the other hand, vitamin A is very sensitive to light, oxygen and heat. Therefore, the protection of vitamin A along with the enhancement of its absorption and bioavailability is highly encouraged. The main goal of the present research is to study the release mechanism and bioavailability of vitamin A from a multilayer WOW emulsion in vitro system. The multilayer WOW emulsion is applied as the delivery system to protect vitamin A and enhance its solubility. The main objective of this study was to investigate the effect of high energy. To the best of our knowledge, there is no published report investigating the release behavior of vitamin A from multilayer WOW emulsion. The output of this study can provide the information about a novel deliver system which can facilitate the controlled release, absorption and bioavailability of vitamin A in the human body. Hence, find the new delivery system in vitamin A and the stability for long-term of consumption.