Journal of Chromatography & Separation Techniques
Open Access
ISSN: 2157-7064
+44 1300 500008
ISSN: 2157-7064
+44 1300 500008
Grazyna Adamus
Posters-Accepted Abstracts: J Chromatogr Sep Tech
Despite of the constant improvement of the synthesis methods, synthetic polymers may show a structural heterogeneity related with topology (linear, cyclic, and branched), composition and comonomers composition distribution (different functional groups, sequence of monomers). This makes the structural and molecular analysis of synthetic polymers quite a complex analytical task. The knowledge of structure-property relationships is essential for the successful application of polymeric materials, especially in biomedical applications such as tissue engineering and delivery system of bioactive compounds and cosmetic modifications. Therefore, there is a continuous require for the development and detailed characterization of new polymeric materials. In this contribution our recent results concerned with application of ESI-MS and electrospray multistage mass spectrometry (ESI-MSn) techniques for advanced structural characterization of new biodegradable polymeric materials based on the aliphatic (co) polyesters will be reported. A new biodegradable polymeric materials with different architecture for potential application as biomaterials for medical and cosmetology purpose were synthesized via. anionic ring opening polymerization (ROP). Furthermore, application of mass spectrometry for monitoring the hydrolytic degradation process of the obtained homo and copolyester, which gave the detailed insights into the hydrolysis process and allowed on identification of the degradation products release from them into the water will be demonstrated.