Maternal risk factors associated with retinopathy of prematurity | 43953
Pediatrics & Therapeutics

Pediatrics & Therapeutics
Open Access

ISSN: 2161-0665

+44 1478 350008

Maternal risk factors associated with retinopathy of prematurity among patients in east avenue medical center from 2010 to 2015

Joint Event on 17th American Pediatrics Healthcare & Infectious Diseases Congress & 17th Annual World Congress on Neonatology

June 27-28, 2018 | Vancouver, Canada

Ida Fidelis Denosta and Carina Cruz-Quimbo

East Avenue Medical Center, Philippines

Posters & Accepted Abstracts: Pediatr Ther

Abstract :

Aim: The aim of this study was to determine the maternal risk factors associated with the development of retinopathy of prematurity (ROP). Design & Setting: A retrospective cohort study. The study was done in a tertiary government hospital. Patients: This study included admitted premature neonates in neonatal intensive care unit (NICU) who underwent ROP screening. All patients with congenital abnormality of the eyes were excluded in the study. Methodology: List of admitted premature patients who underwent ROP screening was collected within the study period. Demographic data was collected from the patient�??s medical records. Statistical Analysis: Descriptive statistics were presented for categorical outcome measures. Wilcoxon rank sum test was used to compare two averages. Chi-square test, Yates�?? chi-square test and Fisher�??s exact test were used to compare proportions. Univariate and multivariate regression analyses were used to estimate crude and adjusted odds-ratios, corresponding 95% CI and based on p-value �?�0.05 statistical significance. Result: This study showed 57% cases of ROP, majority with Stage 1 (66%), mostly female infants (53.4%; p<0.001), mildly asphyxiated (51.2%, p=0.290; 77.2%, p=0.117) and were small for gestational age (57.3%; p<0.001). On the average, these infants underwent one day of either invasive or non-invasive mechanical ventilation, two days with FiO2 of >0.5 liters per minute, had two blood transfusions, and with shorter hospital stay (17 vs 26 days; p<0.001). The average age of mothers who delivered infants with ROP was 26 years old, multipara (59.2%), and underwent normal spontaneous delivery (67%). About half reported adequate prenatal checkups (53.8%) and diagnosed with urinary tract infection (40.1%). Conclusion: Data showed that mothers with urinary tract infection and preeclampsia are more likely to deliver infants with retinopathy of prematurity thus a significant maternal risk factors of ROP.

Biography :