Pediatrics & Therapeutics
Open Access
ISSN: 2161-0665
+44 1478 350008
ISSN: 2161-0665
+44 1478 350008
Zakharova Irina, Klimov Leonid, Kuryaninova Victoria, Dolbnya Svetlana, Kasyanova Anna, Budkevich Roman and Budkevich Elena
Russian Medical Academy of Postgraduate Continuing Study, Russia
Stavropol State Medical University, Russia
North Caucasus Federal University, Russia
Posters & Accepted Abstracts: Pediatr Ther
Aim: Analysis of parathormone (PTH) level in infants depending on suffi ciency of vitamin D (VD). Materials & Methods: 107 children aged 1 month to 3 years have been examined; 50 of them are of the fi rst life year (46.7%), 29 (27.1%) second and 28 (26.2%) the third life year. Donation with Cholecalciferol (CCF) drugs prior to study including children 1 life year was conducted in 30 (60.0%) cases (average dose 655.2�?�?�?±50.3 IU/day), 2 life year in 11 (37.9%) cases (average dose 818.2�?�?�?±154.8 IU/day) and 3 life year in 4 (14.3%) children (dose 500 IU/day). Results: Level of PTH in general group was 20.2 [12.3-25.0] pg/mL, PTH level in children who received CCF drugs was 14.9 [10.7-21.7] pg/mL and in those who did not receive CCF drugs 22.3 [15.9-26.0] pg/mL (p<0.01). Correlation between PTH and CCF intake was r=-0.21, p<0.05. Levels of VD and PTH at the fi rst life year was estimated as 30.0 [16.2-40.3] ng/mL and 16.5 [10.7-23.8] pg/mL; at the second life year 24.0 [21.4-29.3] ng/mL and 20.7 [11.7�?¢�?�?�?�?23.0] pg/mL; at the third life year 20.2 [13.8-22.7] ng/mL and 23.2 [18.0-26.1] pg/mL. Correlation between age and PTH level was r=0.17, p=0.05. Among children with VD defi ciency (25(�?�?�?�?�?)D �?�?�?�?20 ng/mL) PTH level was 22.9 [12.3-26.1] pg/mL; VD defi ciency (25(OH)D 20-30 ng/mL) 22.3 [12.5-24.4] pg/mL; normal suffi ciency (25(�?�?�?�?�?)D�?�?�?�?30 ng/mL) 15.9 [12.4-21.9] pg/mL (p�?�?�?�?0.05). Correlation between levels of VD and PTH was r=-0.18, p=0.05. Conclusion: PTH levels in infants diff er depending on the level of 25(�?�?�?�?�?)D, which is infl uenced by preventive intake of CCF drugs to a great extent.
Zakharova Irina is a Professor from Russian Medical Academy of Postgraduate Study in Moscow. She is a Chief of Department of Pediatric Russian Medical Academy of Postgraduate Continuing Study, Moscow and regular Consultant in Pediatrics in Clinic of Russian President Affairs Management and in many private clinics. She is the Member of Editorial Team of Russian medical journals Consilium Medicum and Medical Advice. She has published more than 500 papers.