Pediatrics & Therapeutics
Open Access
ISSN: 2161-0665
+44 1478 350008
ISSN: 2161-0665
+44 1478 350008
Elif Ozalkaya and Zeynep kamil
Maternity and Children Hospital
Posters & Accepted Abstracts: Pediatr Ther
Objective: To evaluate levatricetem (LEV) efficacy in preterm infants admitted in NICU. Study Design: A retrospective study. A total of 26 preterm infants under 37 gestational week who received levatricetem in NICU within 2 years were included. The results were compared with those of 44 preterm infants from the literature who were given levatricetem. Result: The mean gestational week of the infants receiving levatricetem was found as 26.75±3.37, mean birth weight as 938.04±561.2 and mean dose of levatricetem as 17.0±9.23 mg/kg. Overall seizure control rate with LEV was found as 65%, while seizure control was achieved by 11.5% when it was used as the first drug, 35% as the second drug and 15,3% as the third drug. The incidence of sepsis and intraventricular hemorrhage in seizure etiology was 73% in infants who received levatricetem. No side effect was observed with levatricetem. Conclusion: Seizure control was better achieved with LEV given as the 2nd antiepileptic in premature infants. Further studies with randomization of levatricetem and other antiepileptics in seizure control are needed.
E-mail: elifozalkay@gmail.com