Pediatrics & Therapeutics
Open Access
ISSN: 2161-0665
ISSN: 2161-0665
Peiman Nasri,
Imam Hossein Childrenā??s Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
Scientific Tracks Abstracts: Pediatr Ther
Background: Eating disorders in some infants can be due to the inability to reach a level of relaxation necessary to start the feeding process. Gabapentin (GB) has been proposed as a stabilizer of nerve function in improving this disorder. This study aimed to investigate the effect of GB on improving feeding resistance in infants aged 3–6 months. Materials and Methods: This randomized, controlled, double-blind clinical trial was done on 64 infants aged 3-6 months with feeding resistance who were referred to the pediatric clinics and assigned to two groups of 32. The case group was given a dose of 5 mg/kg of GB in the first week, and if not too much sedation, it was increased to 10 mg/kg in the second week every 8 hours, whereas the control group received a placebo. The number of effective breastfeeding and the volume of formula in cc before and after 2 weeks of drug usage were recorded in both groups. Results: The number of breastfeeding sessions significantly had a higher increase in the GB group compared with placebo (median [IQR]: 1 [0,1] vs. 0 [0,1], P = 0.005) as well as an increase in consumed formula volume (mean ± SD: 42.81 ± 24.49 vs. 18.67 ± 14.57, P = 0.003). Keywords: Feeding resistance, gabapentin, infants.
Dr. Peiman Nasri is a dedicated pediatrician at Imam Hossein Children’s Hospital, affiliated with Isfahan University of Medical Sciences in Iran. He is part of the Department of Pediatrics and a researcher at the Child Growth and Development Research Center, focusing on the primordial prevention of non-communicable diseases. His work aims to improve child health through early intervention and innovative research.