Biosensors as detectors in high performance separation techniques | 52698
Journal of Chromatography & Separation Techniques

Journal of Chromatography & Separation Techniques
Open Access

ISSN: 2157-7064

+44 1300 500008

Biosensors as detectors in high performance separation techniques

International Conference and Expo on Separation Techniques

August 10-12, 2015 San Francisco, USA

Marek Trojanowicz

Institute of Nuclear Chemistry and Technology, Poland

Posters-Accepted Abstracts: J Chromatogr Sep Tech

Abstract :

Biosensors are analytical devices incorporating a biological material e.g. tissue, microorganisms organelles, cell receptors, enzymes, antibodies, nucleic acids etc. intimately associated with or integrated with a physicochemical transducers using optical, electrochemical, thermometric, or piezoelectric properties. They have a solid place in contemporary analytical chemistry, which is evident from their very strong position on the market of analytical instruments, mass production of many of them, uncounted applications in various fields, and a very large research potential directed for this field in academia and industry. This is field of modern science and technology, which immediately adapts current achievements and discoveries in various branches of science, electronics, material science and micromechanics. Hyphenation of biosensing with separation methods can be realized practically with all types of biosensors, and many different electro migration and chromatographic methods. This can be a very efficient way for improvement of selectivity of biosensing, and with suitable design of the flow-through cell and whole measuring setup with online sample processing, it allows also improving sensitivity of whole analytical procedure. Another especially valuable application of this concept is design of multi-analyte detection systems with application of enzymes that catalyze reactions of a group of products, or are inhibited by a group of similar compounds. Especially interesting examples of such systems include, for instance electroantennographic detection in liquid chromatography, olfactory detection in gas chromatography, or single-cell based detection in capillary electrophoresis.

Biography :