Pediatrics & Therapeutics
Open Access
ISSN: 2161-0665
+44 1478 350008
ISSN: 2161-0665
+44 1478 350008
Byanicha Aurora
Sriwijaya University, Indonesia
Posters & Accepted Abstracts: Pediatr Ther
Incidence of cardiovascular disease in adulthood could not be separated from the continuous interaction from infancy through adolescence. Some risk factors for cardiovascular disease occurred since his teens. High level of low-density lipoprotein and cholesterol is oft en indicative of increased risk for cardiovascular disease. Th e ratio of LDL to HDL and total cholesterol to HDL can be used to reveal the risk of it. Th is research is to estimate the infl uence of 12 potential factors and to fi nd association of BMI and waist to hip ratio with the level of LDL to HDL and total cholesterol to HDL ratio. A correlation ratio (ETA) design study using primary data which are gathered prospectively among random adolescents in Jambi whose BMI is underweight, normal, overweight and obese that could participate on the day of the survey. Data on 12 potential factors including daily intake, physical activity and family history were collected three days. We administered a questionnaire and measured BMI and waist to hip ratio to assess statistical relation with the level of LDL to HDL and total cholesterol to HDL ratio. Category of LDL to HDL and total cholesterol to HDL ratio was stratifi ed from high risk and low risk. Examination of lipid profi les was done at the clinical laboratory of Abdul Manap Regional Public Hospital in Jambi. Duration of research was about 3 months. Th e study included 50 people with age span of 16 to 20 years old with all of them had low level of LDL to HDL and total cholesterol to HDL ratio. Most of samples were underweight (42%) resulting low risk for cardiovascular disease as well as normal (24%), overweight (26%) and obese (8%) people. BMI was likely to infl uence the low level of LDL to HDL (�?�?�?�?2=0,705) and total cholesterol to HDL ratio (�?�?�?�?2=0,765), confi rmed statistically signifi cant. 94% samples with low risk category of waist to hip ratio were likely to have low risk for cardiovascular disease. Waist to hip ratio infl uenced the low level of LDL to HDL (�?�?�?�?2=0,003) and total cholesterol to HDL ratio (�?�?�?�?2=0,021). Other factors that associated with the level of LDL to HDL and total cholesterol to HDL ratio were frequency of daily intake including fruit, vegetables and snacking consumption, physical activity and family history of incommunicable disease. Th e strongest association was a relation of the level of LDL to HDL and total cholesterol to HDL ratio with body mass index. By knowing the risk factors, cardiovascular disease can be prevented at earlier age.