Pediatrics & Therapeutics
Open Access

A “sick” rhythm alerts onset of serious vascular disease

Joint Event on 16^th Annual World Congress on Pediatrics & 3^rd Annual World Congress on Pediatric Nutrition, Gastroenterology & Child Development

March 21-22, 2018 | New York, USA

Guillermo Torres Viera

University of Puerto Rico, USA

Posters & Accepted Abstracts: Pediatr Ther

Abstract :

Early detection of cardiac allograft vasculopathy (CAV) presents a challenge to pediatricians since symptoms of myocardial ischemia (eg, classic angina pectoris symptoms) are typically absent or atypical. Although rhythm disturbances are related to CAV, sick sinus syndrome (SSS) remains an elusive sign of vasculopathy. The case study begins with an 18 year old male with history of heart transplant on 2011 secondary to myocarditis and associated dilated cardiomyopathy, presented to our pediatric emergency room due to chest tightness and shoulder pain on exertion without associated fevers, cough, leg swelling, or increased abdominal girth. Cardiac enzymes and electrocardiography (ECG) performed at that time were found within normal limits and patient was discharged home. Three days later, patient awoke from sleep with shortness of breath and dizziness, stating episodes of â�?�?slow beatsâ�? and near-syncope during the previous days precipitated during hot showers. He returned to ER where cardiac monitoring placed and noted with tachycardia/bradycardia paroxysms without ST segment changes on ECG. BNP and Panel Reactive Antibodies were sent and found elevated, therefore patient was transferred to Cardiovascular Center for suspected transplant rejection, allograft vasculopathy, and associated sick sinus syndrome. He was taken to cardiac angiography which revealed severe (>90%) stenosis of multiple segments of right coronary artery requiring bare-metal stent placement with immediate evidence of appropriate revascularization. SSS is defined by ECG abnormalities (eg, bradycardia, sinus pauses, sinus arrest) that occur in association with clinical signs and symptoms. It should be widely recognized and alarm primary physicians of serious underlying vasculopathies, particularly in the pediatric population. guillermo.torres@upr.edu