Journal of Clinical Trials
Open Access
ISSN: 2167-0870
ISSN: 2167-0870
Department of Sports Science and Kinesiology, University of Stuttgart, Allmandring 28, 70569 Stuttgart, Baden-Württemberg, Germany
Research
UC-II® Undenatured Type II Collagen Reduces Knee Joint Discomfort and Improves Mobility in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled Clinical Study
Author(s): Katharina Knaub, Christiane Schön, Wilfried Alt, Shane Durkee, Zainulabedin Saiyed and Vijaya Juturu*
Joint discomfort is a common issue in athletes and healthy, active individuals. The objective of this study was to evaluate the efficacy of UC-II® undenatured type II collagen (Undenatured Collagen) in managing knee joint discomfort and mobility in healthy subjects with Activity-related Joint Discomfort (ArJD). Subjects who reported knee pain of 5 on an 11-point Likert scale while performing a Single-Leg-Step-Down (SLSD) test were randomized to receive placebo (PLA, n=48), or Undenatured Collagen (n=48) for 24 weeks. Joint mobility was measured from the daily step number. Joint discomfort was evaluated using the Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaire, duration of pain during sporting activities and number of steps to reach defined pain levels during the SLSD test. A sub-analysis by gender showed a higher number of daily steps in males from the Undenature.. View More»
DOI:
10.35248/2167-0870.22.12.492