Journal of Probiotics & Health

Journal of Probiotics & Health
Open Access

ISSN: 2329-8901

Van Nedervelde Laurence

Labiris, 1 Avenue Emile Gryson, 1070 Anderlecht, Belgium

  • Research Article   
    Disruption Potential of a Multi-species Oral Biofilm by Probiotics: Preliminary Investigation of a New Bacillus subtilis Strain
    Author(s): Van Vlasselaer Martin, Dillemans Monique and Van Nedervelde Laurence*

    Probiotics may represent an appropriate alternative to oral therapy by specifically targeting pathogens during the successive phases of biofilm “formation”. The aim of this work was to find ways to complement and strengthen this anti-biofilm action through examining the effects of 13 probiotics on the “preformed” three-dimensional biofilm structure. An in vitro dental multi-species biofilm model has been developed using pioneer-colonizing streptococci strains Streptococcus mutans, Streptococcus sobrinus, and Streptococcus oralis subsp. oralis with the addition of Actinomyces naeslundii, to obtain highly heterogeneous strong biofilm architecture. Among the different probiotic genera tested, only the genus Bacillus had a significant disruptive impact on biofilm. B. subtilis NOH (Natto Original Habitat) isolated from a traditional Japanese fermented food (natto) w.. View More»
    DOI: 10.35248/2329-8901.21.9.233

    Abstract HTML PDF